International Journals


  • A. Ballesta,, P. Innominato, R. Dallmann, D. Rand, F. Levi: Systems Chronotherapeutics, Pharmacol Rev, 2017, 69 (2) p;161-199

  • S. Dulong, A. Ballesta, A. Okyar, F. Lévi: Identification of circadian determinants of cancer chronotherapy through in vitro chronopharmacology and mathematical modeling, Molecular Cancer Therapeutics, 2015, 14(9): 2154-64 [PDF].

  • A. Ballesta, Q. Zhou, X. Zhang, H. Lv, JM. Gallo: Multi-scale design of cell type-specific pharmacokinteic/pharmacodynamic models for personalized medicine: application to temozolomide in brain tumors, CPT:pharmacometrics and systems pharmacology, 2014, 3, e112 [PDF].

  • A. Ballesta, J. Clairambault, Physiologically based mathematical models to optimize therapies against metastatic colorectal cancer: a mini-review, Current Pharmaceutical Design, 2013 Mar [Abstract]

  • A. Ballesta, M. Doumic-Jauffret, J. Lopez, P. Gonzalo, G. Gillet: Modeling Src control on the mitochondrial pathway of apoptosis, implications for cancer therapeutics, PLoS Computational Biology, 2013 Apr;9(4):e1003011 [PDF]

  • A. Ballesta, S. Dulong, A. Okyar, C. Abbara, B. Cohen, J. Clairambault , F. Lévi: A combined biological and mathematical approach for studying the circadian control of the anticancer drug Irinotecan Pharmacokinetics-Pharmacodynamics at a molecular level, PLoS Computational Biology, 2011 Sep;7(9):e1002143  [PDF]

  • A. Ballesta, J. Clairambault, S. Dulong, F. Lévi: Theoretical Optimization of Irinotecan-based Anticancer Strategies in case of Drug-induced Efflux, Applied Mathematics Letters, 2011 Jul ; 24 (7): 1251-1256 [PDF]
  • S. Prigent, A. Ballesta, F. Charles, N. Lenuzza, P. Gabriel, L. M. Tine, H. Rezaei, M. Doumic: An Efficient Kinetic Model for Assemblies of Amyloid Fibrils and Its Application to Polyglutamine Aggregation, PLoS One2012; 7(11):e43273 [PDF]

  • F Thomas, D. Fisher,... , A. Ballesta,... , Urszula Hibner, Michael Hochberg: Applying ecological and evolutionary theory to cancer: a long and winding road, Evolutionary Applications, 2012 Nov;  doi:10.1111/eva.12021 [PDF]

Book Chapters

  • A. Ballesta, J. Clairambault, S. Dulong, F. Levi: A systems biomedicine approach for chronotherapeutics optimization: focus on the anticancer drug irinotecan. In: New Challenges for Cancer Systems Biomedicine, SIMAI Lecture Notes, Springer, 2012, ISBN 978-88-470-2571-4 [PDF] 
  • E. Ortiz, A. Mteyrek, A. Ballesta, P. Innominato, F. Levi: Circadian timing in cancer treatments. In: Circadian Clocks, Handbook of Experimental Pharmacological Series, Springer, 2013; (217), pp 261-88, ISBN 978-3-642-25950-0 [Abstract]
  • J.L. Avila, C. Bonnet, J. Clairambault, H. Ozbay, S.I. Niculescu, F. Merhi, A. Ballesta, R. Tang and J.P. Marie: Analysis of a new model of cell population dynamics in Acute Myeloid Leukemia. In: Advances in Delays and Dynamics, Springer, 2014, ISBN 2197-117X.

Scientific vulgarization movies

  • A. Ballesta : "Soyez sympas, synchronisez !", short movie on my PhD thesis in the context of the “Les Chercheurs font leur cinema” festival (Université Paris 6), 2009, [French version]
  • A. Ballesta , Inria Paris-Rocquencourt in collaboration with Sydo and Little Worlds: Serious game "Chronotherapie" [PC version] [MAC version]